• Duración:
    11 semanas
  • Dedicación:
    3–6 horas por semana
  • Precio:

    GRATIS
    Add a Verified Certificate for $150 USD

  • Institución
  • Tema:
  • Nivel:
    Intermediate
  • Idioma:
    English
  • Transcripción de video:
    English

Prerrequisitos

Undergraduate introductory biology (biochemistry and molecular biology);
Undergraduate introductory chemistry;
Undergraduate organic chemistry I (chemical structures and biological mechanisms)

Sobre este curso

Do you want to prepare for medical school, study a STEM field, become a research scientist, or transition to a career in the booming biotechnology industry? Or maybe you just want to understand the chemical reactions that govern life itself. Join Professor Yaffe, an MIT professor and practicing surgeon, as he guides you through the science that inspires countless doctors, researchers, and students alike.

We developed 7.05x Biochemistry with an emphasis on:
  • Developing your scientific thinking skills including articulating hypotheses, performing thought experiments, interpreting data, and designing experiments.
  • Using data based on real scientific experiments and highlighting the scientific process.
  • Asserting that biology is an active field that changes daily through examples of MIT (and other current) research, not static information in a textbook.
  • Visualizing real molecular structures with PyMOL to better understand function and mechanism.
  • Appreciating the quantitative aspects of biochemistry and practicing this quantitation with MATLAB.
  • Translating topics in biochemistry to diseases and medicine.  
  • Conveying the authentic MIT firehose experience.
  • Implementing the science of learning in the course design.
We offer a thorough and robust means of certifying edX learners in their mastery of the MITx biochemistry content, through the MITx 7.05x Biochemistry Competency Exam. This challenging option is available only to those who register for the verified-certificate track, and successful completion of this exam is the majority of the assessment grade that counts toward a certificate. The Competency Exam will be open from August 20, 2019 to August 27, 2019.

Lo que aprenderás

  • How to apply the scientific method to pursue research questions.
  • How to analyze protein purification schemes.
  • How scientists determine the structure of a protein.
  • How structure, allostery, and the Bohr effect influence hemoglobin function.
  • How to interpret graphs, plot behaviors, and calculate constants related to enzyme function.
  • How pumps, transporters, and channels differ to regulate molecule transfer across membranes.
  • How G proteins play a key role in signaling.
The course includes the following learning sequences:
  • Introduction to Biochemistry; pH and Buffers
  • Amino Acids and Proteins
  • Protein Purification
  • Protein Structure 
  • Protein Folding
  • Hemoglobin and Allostery
  • Hemoglobin and the Bohr Effect
  • Enzyme Chemistry
  • Enzyme as Catalysts
  • Enzyme Kinetics
  • Membranes, Channels, Transporters, and Pumps
  • Blood Clotting
  • Signal Transduction

Conoce a tus instructores

Michael Yaffe
Director, MIT Center for Precision Cancer Medicine; David H. Koch Professor in Science; Professor of Biological Engineering
Massachusetts Institute of Technology
Mary Ellen Wiltrout
MITx Digital Learning Scientist, Department of Biology
Massachusetts Institute of Technology
Darcy Gordon
MITx Digital Learning Fellow, Department of Biology
Massachusetts Institute of Technology
Monika Avello
MITx Digital Learning Fellow, Department of Biology
Massachusetts Institute of Technology

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Testimonios de los estudiantes

In short, if you enjoy the opportunity to 'virtually' study at a very high level with some of the finest practitioners in their field, this is among the very best courses available to engage that passion.” – Class Central learner review

For 1.5 hours three times a week, hundreds of students fill 10-250 (one of the giant lecture halls) to watch Yaffe cover crazy amounts of information in very little time. By the end of every lecture, you probably have four pages of very colorful notes and 9 boards filled with pretty picture of molecules and processes.” – MIT student blogger

¿Quién puede hacer este curso?

Lamentablemente, las personas de uno o más de los siguientes países o regiones no podrán registrarse para este curso: Irán, Cuba y la región de Crimea en Ucrania. Si bien edX consiguió licencias de la Oficina de Control de Activos Extranjeros de los EE. UU. (U.S. Office of Foreign Assets Control, OFAC) para ofrecer nuestros cursos a personas en estos países y regiones, las licencias que hemos recibido no son lo suficientemente amplias como para permitirnos dictar este curso en todas las ubicaciones. edX lamenta profundamente que las sanciones estadounidenses impidan que ofrezcamos todos nuestros cursos a cualquier persona, sin importar dónde viva.