• Duración:
    7 semanas
  • Dedicación:
    4–8 horas por semana
  • Precio:

    GRATIS
    Agregar un Certificado Verificado por $99 USD

  • Institución
  • Tema:
  • Nivel:
    Advanced
  • Idioma:
    English
  • Transcripciones de video:
    English, 中文
  • Tipo de curso:
    A tu ritmo

Prerrequisitos

7.00x Introduction to Biology or similar (undergraduate biochemistry, molecular biology, and genetics) and 7.28.1x Molecular Biology or similar (advanced DNA replication and repair)

Sobre este curso

Omitir Sobre este curso

In Part 2 of this Molecular Biology course, you’ll explore transcription of DNA to RNA, a key part of the central dogma of biology and the first step of gene expression.

Did you know that transposable elements, the genetic information that can move from location to location, make up roughly 50 % of the human genome? Did you know that scientists have linked their movement into specific genes to the causes of certain diseases? You’ll also learn how these “jumping genes” work and how scientists study them in Molecular Biology: Transcription and Transposition.

Are you ready to go beyond the “what" of scientific information presented in textbooks and explore how scientists deduce the details of these molecular models?

Take a behind-the-scenes look at modern molecular genetics, from the classic experimental events that identified the proteins and elements involved in transcription and transposition to cutting-edge assays that apply the power of genome sequencing. We've designed the problems in this course to build your experimental design and data analysis skills.

Let’s explore the limits of our current knowledge about the transcription machinery and mechanisms of transposition. If you are up for the challenge, join us in 7.28.2x Molecular Biology: Transcription and Transposition.

Lo que aprenderás

Omitir Lo que aprenderás
  • How to compare and contrast transcription in prokaryotes and eukaryotes
  • How to describe several mechanisms of transposition
  • How to analyze protein structures to infer functional information
  • How todesign the best experiment to test a hypothesis
  • How to interpret data from transcription and transposition experiments

Plan de estudios

Omitir Plan de estudios

Week 1 : Machinery and Promoters of Bacterial Transcription

Week 2 : Bacterial Regulation of Bacterial Transcription

Week 3 : Machinery and Promoters of Eukaryotic Transcription

Week 4 : Regulation of Eukaryotic Transcription I

Week 5 : Regulation of Eukaryotic Transcription II

Week 6 : Transposition

Week 7 : CRISPR

Conoce a tus instructores

Stephen P. Bell
HHMI Investigator; Professor of Biology
MIT
Tania A. Baker
HHMI Investigator; Whitehead Professor of Biology
MIT
Mary Ellen Wiltrout
Director of Blended and Online Initiatives, Lecturer, Department of Biology
Massachusetts Institute of Technology
Nathaniel Schafheimer
MITx Digital Learning Fellow, Department of Biology
MIT

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Preguntas frecuentes

Who can take this course?

Unfortunately, learners from one or more of the following countries or regions will not be able to register for this course: Iran, Cuba and the Crimea region of Ukraine.While edX has sought licenses from the U.S. Office of Foreign Assets Control (OFAC) to offer our courses to learners in these countries and regions, the licenses we have received are not broad enough to allow us to offer this course in all locations. EdX truly regrets that U.S. sanctions prevent us from offering all of our courses to everyone, no matter where they live.

¿Quién puede hacer este curso?

Lamentablemente, las personas de uno o más de los siguientes países o regiones no podrán registrarse para este curso: Irán, Cuba y la región de Crimea en Ucrania. Si bien edX consiguió licencias de la Oficina de Control de Activos Extranjeros de los EE. UU. (U.S. Office of Foreign Assets Control, OFAC) para ofrecer nuestros cursos a personas en estos países y regiones, las licencias que hemos recibido no son lo suficientemente amplias como para permitirnos dictar este curso en todas las ubicaciones. edX lamenta profundamente que las sanciones estadounidenses impidan que ofrezcamos todos nuestros cursos a cualquier persona, sin importar dónde viva.