• Duración:
    4 semanas
  • Dedicación:
    2–4 horas por semana
  • Precio:

    GRATIS
    Agregar un Certificado Verificado por $249 USD

  • Institución
  • Tema:
  • Nivel:
    Intermediate
  • Idioma:
    English
  • Transcripción de video:
    English
  • Tipo de curso:
    A tu ritmo

Programas asociados:

Prerrequisitos

  • Basic programming
  • Basic math

Sobre este curso

Omitir Sobre este curso

This course teaches the R programming language in the context of statistical data and statistical analysis in the life sciences.

We will learn the basics of statistical inference in order to understand and compute p-values and confidence intervals, all while analyzing data with R code. We provide R programming examples in a way that will help make the connection between concepts and implementation. Problem sets requiring R programming will be used to test understanding and ability to implement basic data analyses. We will use visualization techniques to explore new data sets and determine the most appropriate approach. We will describe robust statistical techniques as alternatives when data do not fit assumptions required by the standard approaches. By using R scripts to analyze data, you will learn the basics of conducting reproducible research.

Given the diversity in educational background of our students we have divided the course materials into seven parts. You can take the entire series or individual courses that interest you. If you are a statistician you should consider skipping the first two or three courses, similarly, if you are biologists you should consider skipping some of the introductory biology lectures. Note that the statistics and programming aspects of the class ramp up in difficulty relatively quickly across the first three courses. We start with simple calculations and descriptive statistics. By the third course will be teaching advanced statistical concepts such as hierarchical models and by the fourth advanced software engineering skills, such as parallel computing and reproducible research concepts.

These courses make up 2 XSeries and are self-paced:

PH525.1x: Statistics and R for the Life Sciences

PH525.2x: Introduction to Linear Models and Matrix Algebra

PH525.3x: Statistical Inference and Modeling for High-throughput Experiments

PH525.4x: High-Dimensional Data Analysis

PH525.5x: Introduction to Bioconductor: annotation and analysis of genomes and genomic assays

PH525.6x: High-performance computing for reproducible genomics

PH525.7x: Case studies in functional genomics

This class was supported in part by NIH grant R25GM114818.

Lo que aprenderás

Omitir Lo que aprenderás
  • Random variables
  • Distributions
  • Inference: p-values and confidence intervals
  • Exploratory Data Analysis
  • Non-parametric statistics

Conoce a tus instructores

Rafael Irizarry
Professor of Biostatistics
Harvard University
Michael Love
Assistant Professor, Departments of Biostatistics and Genetics
UNC Gillings School of Global Public Health

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