This curriculum includes research into fundamental knowledge of clinical diagnosis, prevention and treatment of COVID-19. Different strategies for drug development targeting this virus, the specific virus-host interaction of COVID-19 and how artificial intelligence (AI) contributes to the drug discovery will also be introduced during our lessens. In addition, Tsinghua University now open free access to researchers, clinicians and policymakers, hoping to offer some insights to responders around the world to be better equipped.