About this course
We developed 7.05x Biochemistry with an emphasis on:
- Developing your scientific thinking skills including articulating hypotheses, performing thought experiments, interpreting data, and designing experiments.
- Using data based on real scientific experiments and highlighting the scientific process.
- Asserting that biology is an active field that changes daily through examples of MIT (and other current) research, not static information in a textbook.
- Visualizing real molecular structures with PyMOL to better understand function and mechanism.
- Appreciating the quantitative aspects of biochemistry and practicing this quantitation with MATLAB.
- Translating topics in biochemistry to diseases and medicine.
- Conveying the authentic MIT firehose experience.
- Implementing the science of learning in the course design.
What you'll learn
- How to apply the scientific method to pursue research questions.
- How to analyze protein purification schemes.
- How scientists determine the structure of a protein.
- How structure, allostery, and the Bohr effect influence hemoglobin function.
- How to interpret graphs, plot behaviors, and calculate constants related to enzyme function.
- How pumps, transporters, and channels differ to regulate molecule transfer across membranes.
- How G proteins play a key role in signaling.
- Introduction to Biochemistry; pH and Buffers
- Amino Acids and Proteins
- Protein Purification
- Protein Structure
- Protein Folding
- Hemoglobin and Allostery
- Hemoglobin and the Bohr Effect
- Enzyme Chemistry
- Enzyme as Catalysts
- Enzyme Kinetics
- Membranes, Channels, Transporters, and Pumps
- Blood Clotting
- Signal Transduction
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“For 1.5 hours three times a week, hundreds of students fill 10-250 (one of the giant lecture halls) to watch Yaffe cover crazy amounts of information in very little time. By the end of every lecture, you probably have four pages of very colorful notes and 9 boards filled with pretty picture of molecules and processes.” – MIT student blogger
Who can take this course?
Unfortunately, learners from one or more of the following countries or regions will not be able to register for this course: Iran, Cuba and the Crimea region of Ukraine. While edX has sought licenses from the U.S. Office of Foreign Assets Control (OFAC) to offer our courses to learners in these countries and regions, the licenses we have received are not broad enough to allow us to offer this course in all locations. EdX truly regrets that U.S. sanctions prevent us from offering all of our courses to everyone, no matter where they live.