Assistant Professor in the Division of Toxicology at Wageningen University & Research
Areas of expertise
- In vitro toxicology
- Developmental toxicity
- Physiologically-based kinetic modelling
- Stem cells
- Louisse J, De Jong E, van de Sandt JJM, Blaauboer BJ, Woutersen RA, Piersma AH, Rietjens IMCM, Verwei M (2010). The use of in vitro toxicity data and physiologically based kinetic modeling to predict dose-response curves for in vivo developmental toxicity of glycol ethers in rat and man. Toxicol Sci. 118: 470-484.
- Louisse J, Verwei M, Woutersen RA, Blaauboer BJ, Rietjens IMCM (2012). Toward in vitro biomarkers for developmental toxicity and their extrapolation to the in vivo situation. Expert Opin Drug Metab Toxicol.8:11-27.
- Louisse J, Bosgra S, Blaauboer BJ, Rietjens IMCM, Verwei M (2015). Prediction of in vivo developmental toxicity of all-trans-retinoic acid based on in vitro toxicity data and in silico physiologically based kinetic modeling. Arch Toxicol. 89:1135-1148.
Dr. Jochem Louisse is Assistant Professor in the Division of Toxicology at Wageningen UR. He is both a Dutch and European Registered Toxicologist (ERT). He received his MSc in Biology and PhD in Toxicology from Wageningen University in 2007 and 2012, respectively. His research focuses on the development of non-animal test methods to perform toxicity studies. He does so, by developing human cell-based models combined with computer modelling.