This course includes the following 11 lectures:

Overview of Design Options for Pragmatic Clinical Trials
Outcome Measures in Clinical Trials
Non-inferiority Trials
Basic Analytic Methods
Basic Power and Sample Size Calculations
SMART: Adaptive Treatment Strategies
Introduction to Bayesian Methods
Bayesian Designs
Quasi-Experiment in Health Services Research
Adaptive Trial Design
Logistics of Clinical Trials

This course is intended for anyone interested in comparative effectiveness research (CER) and patient-centered outcomes research (PCOR) methods.

This course is supported by grant number R25HS023214 from the Agency for Healthcare Research and Quality.

42:T5a2,

While randomized controlled trials are considered to be the "gold standard" in health research, they cannot always be performed, for ethical or practical reasons. Observational studies gather information from data that has already been collected, or by observing and measuring patients' changes in health status and their response to interventions outside of a clinical trial. In this course, you will learn to identify the characteristics of observational studies, to interpret the results of observational studies, and to describe the use of health registries in comparative effectiveness research (CER).

This course includes the following 11 lectures:

Overview of Using Observational Data in Comparative Effectiveness Research (CER)
Cancer Registries and Data Linkage
SEER-Medicare and Other Data Sources
Overview of Analytic Methods I
Overview of Analytic Methods II
Longitudinal Data Analysis
Advanced Methods in CER I
Advanced Methods in CER II
Survival Analysis
Analysis of Medical Cost Data in Observational Studies
Healthcare Policy Research

This course is intended for anyone interested in comparative